If you want to be extra careful, go ahead and power your device down completely.
Lint-free cloths meant to clean eye glasses work well but any microfiber cloth will do.
Dust the screen as often as you’d like, just remember to be gentle!
Most Apple devices have a thin glass layer over their LCD screens. PC desktops and laptops usually don’t. The only way to know for sure is to check the user manual or manufacturer’s website for information on your specific device. Most warranties won’t be honored by the manufacturer if you damage an LCD screen with liquid or cleaner. [5] X Research source
Plus, it’s easier to see smudges and gunk when the screen is totally black.
This is usually safe to do on most LCD screens unless the manufacturer specifically says not to. Using tap water occasionally isn’t a big deal, but distilled water is preferable since it doesn’t contain minerals. [9] X Research source
For most devices, soap and water is fine as long as you don’t do it often. Give the screen a few minutes to dry before turning the device back on. If you want to disinfect your screen, soap and water isn’t a good option. In fact, a dry lint-free cloth will remove more germs than soap and water.
Never spray LCD cleaner directly on the screen since the liquid can trickle down into the screen frame and damage it. [12] X Research source Do not use commercial cleaners with alcohol in them. If you want to sanitize your screen, LCD cleaner probably will not be effective.
Vinegar has sanitizing properties so it may kill some germs on the surface. Keep in mind this probably isn’t as effective as a Lysol wipe at killing germs. Allow the screen to dry or wipe it gently with a dry microfiber cloth before turning it back on.
Letting the surface dry first prevents electrical shock and also gives the Lysol time to destroy the germs on the surface. Do not use Lysol wipes to kill germs on a regular PC monitor or any LCD screen without a glass coating. For those, water or a vinegar solution are your best bets.