Mice do not like water, so make sure the washcloth is not too soaked! It should be damp. [2] X Research source Be careful to not make the water hot or cold, as either end can upset a mouse’s skin if directly applied. Choose the softest washcloth available to you.

Do not forget to clean the feet! The feet can trap a lot of icky waste, which can contribute to the mouse’s smelliness. Be careful of the mouse’s eyes, nose, and ears. These are especially delicate areas. [4] X Research source

Do not apply puppy shampoo directly to the mouse. Add the shampoo to water, which you can then dip your washcloth into. Ring out any excess. [6] X Research source Use a tiny amount of puppy shampoo. You will not need more than a few drops. [7] X Research source If the smell is not going away, it is likely that your mouse has a health issue. Take it to a veterinarian to get examined. [8] X Research source

Do not use hot or cold water. It should be warm. Ring out any excess water before applying the washcloth to the mouse.

Use a soft washcloth, as a harsh one can hurt the mouse. Do not air-dry or blow-dry the mouse. Air-drying keeps the mouse wet for longer and blow-drying can hurt a mouse’s ears. [11] X Research source

For daily cleaning, you can just remove wet or soiled areas. [14] X Research source

You can get disinfectant at your local pet store, grocery store, or online. If you cannot get disinfectant, you can use a water-soap mixture as a temporary substitute. [16] X Research source Make sure you dry the cage completely. A damp cage will add unwanted moisture to the new bedding. [17] X Research source

If the manufacturer of the toys or accessories gives specific cleaning instructions, follow them. [19] X Research source

Do not use pine or cedar wood shavings. They can release fumes that can make your mouse ill. [21] X Research source You can add shredded paper towels or straw to the bedding. These are soft materials that can also be used by your mouse to make a comfy nest. Do not put newspaper in the mouse’s cage because the ink can rub off. [22] X Research source

Once you’ve done this, you can put your mouse back in its fresh, clean home!